The first thinkers ever to ask, in anything like their modern form, such radical and demythologised questions as what is the world made of? and how does it change? were the Pre-Socratic philosophers of Ancient Greece (operating between roughly 600 and 400BCE). Their intellectual ingenuity and daring remains one of the great landmarks in human achievement. It gave rise to an atomic theory, Pythagoras Theorem, and geometric techniques good enough to obtain a reasonable estimate of the circumference of a (spherical) Earth.
Nevertheless the Greeks did not go on to invent experimental science. This is partly because their philosophy became dominated by two patterns of thinking both extremely ingenious, but neither propitious for science:
Platos idealism, the conviction that the perfect abstraction is more real and worthier of study than a physical entity which may crudely imitate the abstraction, and
Aristotles theory of causation, which included not only material causes (what things are made of) and efficient causes (what past events affected them) but also formal causes (to what pattern the matter in them conforms) and final causes (towards what purpose or end are things being attracted).
To say that Plato and Aristotle of
themselves do not lead to experimental science is not however to deny their
enormous contribution in framing and training the patterns of thought of the
Western world from their own time until now. For instance, Aristotles texts on
logic, metaphysics
and the structure of the world were a major spur to intellectual development in
the late Middle Ages. Importantly, these great Aristotelian texts entered Western Europe through the work of
Islamic commentators.
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Source: God, Humanity and the Cosmos (T&T Clark, 1999)